Genomic representations using concatenates of Type IIB restriction endonuclease digestion fragments.
نویسندگان
چکیده
We have developed a method for genomic representation using Type IIB restriction endonucleases. Representation by concatenation of restriction digests, or RECORD, is an approach to sample the fragments generated by cleavage with these enzymes. Here, we show that the RECORD libraries may be used for digital karyotyping and for pathogen identification by computational subtraction.
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ورودعنوان ژورنال:
- Nucleic acids research
دوره 32 15 شماره
صفحات -
تاریخ انتشار 2004